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Zevalin Y-90: Benefits, Reviews, Info, Side Effects!
Rx Details
Zevalin Y-90
Yttrium-90 ibritumomab tiuxetan
Ibritumomab tiuxetan
Prescription
Radiopharmaceutical
Drugs
Radioactive therapeutic agent
radioimmunotherapy treatment, targets CD20 antigen, treats non-Hodgkin’s lymphoma, delivers targeted radiation, reduces tumor size, can be used after other treatments, potential for remission, outpatient procedure, short treatment duration
Abdominal Pain, Bleeding, Bruising, Chills, Cough, Diarrhea, Dizziness, Fatigue, Fever, Headache, Infections, Itching, Joint Pain, Low Blood Cell Counts, Muscle Pain, Nausea, Rash, Shortness Of Breath, Vomiting, Weakness
Zevalin Y-90 (Ibritumomab tiuxetan) is a radiopharmaceutical used in the treatment of certain types of non-Hodgkin’s lymphoma. The dosage of Zevalin Y-90 is not a straightforward milligram or microgram amount like many other drugs, as it involves a complex dosing regimen based on the patient’s body weight and platelet count. The typical dosing regimen for Zevalin Y-90 involves two main components: 1. **Rituximab Pre-treatment**: Patients first receive an infusion of rituximab, a monoclonal antibody, to help target the lymphoma cells. 2. **Yttrium-90 Zevalin Dose**: The dose of Y-90 Zevalin is calculated based on the patient’s body weight and platelet count. Generally, the dose is 0.4 mCi/kg (millicuries per kilogram) of body weight for patients with a platelet count of at least 150,000 cells/mm³. For patients with a platelet count between 100,000 and 149,000 cells/mm³, the dose is reduced to 0.3 mCi/kg. The maximum allowable dose is typically capped at 32 mCi. It’s important to note that the administration of Zevalin Y-90 should be conducted by a healthcare professional experienced in the use of radiopharmaceuticals, and the exact dosage should be determined by the treating physician based on individual patient factors.
Non-hodgkin’s lymphoma
Zevalin Y-90 has a generally safe safety profile.
Chemotherapy, radiation therapy, immunotherapy
$10,000 – $15,000
$20,000

A Synopsis of

Zevalin Y-90

Zevalin Y-90 is a targeted radioimmunotherapy drug used in the treatment of certain types of non-Hodgkin’s lymphoma. This medication combines the power of a monoclonal antibody with the radioactive isotope Yttrium-90 to specifically target and destroy cancerous B-cells in the body.

Zevalin Y-90 works by attaching itself to a protein called CD20, which is found on the surface of B-cells. Once attached, the radioactive Yttrium-90 emits radiation that directly targets and kills the cancerous cells while sparing healthy surrounding tissue. This targeted approach helps to minimize side effects and improve the overall effectiveness of the treatment.

Patients receiving Zevalin Y-90 may experience some common side effects such as fatigue, nausea, and low blood cell counts. It is important for patients to discuss any concerns or side effects with their healthcare provider to ensure proper management and support throughout treatment.

As with any medication, it is important for patients to follow their healthcare provider’s instructions carefully and attend all scheduled appointments for monitoring and follow-up. Zevalin Y-90 is typically administered in a specialized healthcare setting by trained professionals who are experienced in radioimmunotherapy.

Overall, Zevalin Y-90 has shown promising results in the treatment of non-Hodgkin’s lymphoma and offers a targeted approach to destroying cancerous cells while minimizing damage to healthy tissue. If you have been prescribed Zevalin Y-90 or are considering this treatment option, be sure to discuss any questions or concerns with your healthcare provider to determine if this medication is right for you.

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