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Sitagliptin & Metformin: Benefits, Reviews, Info, Side Effects!
Rx Details
Sitagliptin & Metformin
Janumet, Janumet XR, Jentadueto, Velmetia
Sitagliptin is the chemical name for Januvia, and Metformin is the chemical name for Glucophage.
Prescription
Medication
Drugs
Prescription Only
Improved blood sugar control, reduced risk of cardiovascular events, weight neutrality, low risk of hypoglycemia, potential improvement in beta-cell function, convenient combination therapy, potential reduction in insulin resistance.
Abdominal Pain, Diarrhea, Flatulence, Headache, Hypoglycemia, Lactic Acidosis, Metallic Taste, Nausea, Upper Respiratory Tract Infection, Vitamin B12 Deficiency, Vomiting, Weakness
Sitagliptin and metformin are often combined in a single medication to treat type 2 diabetes. The average dosage can vary based on individual patient needs, but a common starting dose for the combination medication (often marketed under the brand name Janumet) is: – Sitagliptin 50 mg / Metformin 500 mg or 1000 mg, taken twice daily. Dosage may be adjusted by healthcare providers based on the patient’s response to treatment, kidney function, and other factors. It’s important for patients to follow their healthcare provider’s instructions regarding dosage.
Type 2 diabetes
Generally well-tolerated, common side effects include diarrhea and nausea.
No Interactions Reported
$10.99 – $49.99
$33.75

A Synopsis of

Sitagliptin & Metformin

Sitagliptin and Metformin are two commonly prescribed medications used in the treatment of type 2 diabetes. Sitagliptin belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors, while Metformin is a biguanide medication. When used together, these two drugs work synergistically to help control blood sugar levels in patients with diabetes.

Sitagliptin works by increasing the levels of incretin hormones in the body, which help to stimulate the release of insulin and inhibit the production of glucagon. This results in lower blood sugar levels after meals. Metformin, on the other hand, works by decreasing the amount of glucose produced by the liver and improving the body’s sensitivity to insulin.

By combining Sitagliptin and Metformin, patients with type 2 diabetes can benefit from the complementary mechanisms of action of these two medications. This combination therapy can help improve glycemic control, reduce the risk of complications associated with diabetes, and ultimately improve the overall quality of life for patients.

It is important to note that like all medications, Sitagliptin and Metformin may cause side effects in some individuals. Common side effects may include gastrointestinal symptoms such as nausea, diarrhea, and abdominal discomfort. It is important for patients to discuss any concerns or side effects with their healthcare provider.

Overall, Sitagliptin and Metformin are valuable treatment options for individuals with type 2 diabetes. When used as prescribed and in conjunction with a healthy lifestyle, these medications can help patients better manage their condition and improve their overall health outcomes.

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