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Secukinumab: Benefits, Reviews, Info, Side Effects!
Rx Details
Secukinumab
Cosentyx, Amevive
Secukinumab
Prescription
Biologic
Drugs
Prescription Only
reduction of inflammation, improvement of psoriasis symptoms, relief from psoriatic arthritis, reduction of ankylosing spondylitis symptoms, improvement in quality of life, reduction in plaque psoriasis severity, improvement in joint function
Back Pain, Diarrhea, Fatigue, Headache, Hypertension, Injection Site Reactions, Nausea, Oral Herpes, Rhinorrhea, Upper Respiratory Tract Infections
Secukinumab, marketed under the brand name Cosentyx, is a monoclonal antibody used to treat autoimmune conditions such as plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. The dosage of Secukinumab can vary based on the condition being treated: 1. **Plaque Psoriasis**: – Initial dose: 300 mg administered by subcutaneous injection at weeks 0, 1, 2, 3, and 4. – Maintenance dose: 300 mg every 4 weeks. 2. **Psoriatic Arthritis**: – For patients with concomitant moderate to severe plaque psoriasis or those who are anti-TNF inadequate responders, the dosage is the same as for plaque psoriasis. – For other patients, the recommended dose is 150 mg by subcutaneous injection at weeks 0, 1, 2, 3, and 4, followed by 150 mg every 4 weeks. Some patients may benefit from a dose of 300 mg. 3. **Ankylosing Spondylitis**: – Initial dose: 150 mg by subcutaneous injection at weeks 0, 1, 2, 3, and 4. – Maintenance dose: 150 mg every 4 weeks. It’s important to follow the specific dosing instructions provided by a healthcare professional, as they may adjust the dosage based on individual patient needs and response to treatment.
Psoriasis, psoriatic arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis
Secukinumab has a generally favorable safety profile.
No Interactions Reported
$1,500 – $2,000
$5,500 for a 150mg/mL syringe.

A Synopsis of

Secukinumab

Secukinumab is a medication that belongs to a class of drugs known as biologics, specifically targeting a protein in the body called interleukin-17A. This protein plays a key role in the inflammatory response that is associated with conditions such as psoriasis, psoriatic arthritis, and ankylosing spondylitis.

Secukinumab works by blocking the action of interleukin-17A, thereby reducing inflammation and symptoms associated with these conditions. It is administered as an injection under the skin, typically once a month, and has been shown to be effective in improving skin symptoms in patients with moderate to severe plaque psoriasis, as well as reducing joint pain and swelling in those with psoriatic arthritis and ankylosing spondylitis.

As with any medication, there are potential side effects to be aware of when taking secukinumab. These can include injection site reactions, upper respiratory infections, and an increased risk of certain infections. It is important to discuss any concerns or potential side effects with your healthcare provider before starting treatment with secukinumab.

Overall, secukinumab has been shown to be a valuable treatment option for individuals suffering from inflammatory conditions such as psoriasis, psoriatic arthritis, and ankylosing spondylitis. It is important to follow your healthcare provider’s instructions for proper administration and monitoring while taking this medication to ensure the best possible outcomes. If you have any questions or concerns about secukinumab or its use, do not hesitate to reach out to your healthcare provider for guidance.

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