Ribociclib, also known by its brand name Kisqali, is a medication used in combination with letrozole for the treatment of hormone receptor-positive, HER2-negative advanced breast cancer in postmenopausal women. Ribociclib works by inhibiting specific proteins in cancer cells that are involved in cell division and growth, thereby slowing down the progression of the disease.

Letrozole is an aromatase inhibitor that works by reducing the production of estrogen in the body, which can help slow down or stop the growth of hormone receptor-positive breast cancer cells. When used in combination with ribociclib, letrozole can be even more effective in treating advanced breast cancer.

It is important to follow your healthcare provider’s instructions when taking ribociclib and letrozole. These medications are typically taken orally once a day, with or without food. It is important to take them at the same time each day to maintain a consistent level of the medication in your body.

Like all medications, ribociclib and letrozole can cause side effects. Common side effects of ribociclib may include nausea, fatigue, diarrhea, and decreased appetite. Letrozole may cause hot flashes, joint pain, and fatigue. It is important to discuss any side effects you may experience with your healthcare provider.

If you have been prescribed ribociclib and letrozole for the treatment of advanced breast cancer, it is important to stay in close communication with your healthcare team. They can monitor your progress, adjust your treatment plan as needed, and provide support throughout your journey. Remember, you are not alone in this fight against cancer.