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Palynziq: Benefits, Reviews, Info, Side Effects!
Rx Details
Palynziq
Pegvaliase, PEGylated phenylalanine ammonia lyase
Pegvaliase
Prescription
Enzyme
Drugs
Prescription Only
reduces blood phenylalanine levels, treats phenylketonuria (PKU), improves metabolic control, allows more dietary freedom, enhances quality of life
Abdominal Pain, Cough, Diarrhea, Dizziness, Fatigue, Fever, Headache, Injection Site Reactions, Joint Pain, Nausea, Rash, Throat Pain, Vomiting
Palynziq (pegvaliase-pqpz) is a medication used to treat adults with phenylketonuria (PKU) who have uncontrolled blood phenylalanine (Phe) levels. The dosing of Palynziq is individualized and typically involves a titration phase to determine the appropriate maintenance dose for each patient. The typical dosing schedule starts with a low dose and gradually increases over several weeks. The initial dosing might begin at 2.5 mg once weekly, and then gradually increase to 10 mg once daily, and potentially up to 20 mg or 40 mg once daily, depending on the patient’s response and tolerability. It’s important to follow the specific dosing instructions provided by a healthcare professional, as the dosage can vary based on individual needs and response to the treatment. Regular monitoring of blood Phe levels is necessary to adjust the dosage appropriately.
Phenylketonuria
Palynziq has a known safety profile.
No Interactions Reported
$10,000 – $20,000
$58,000

A Synopsis of

Palynziq

Palynziq is a breakthrough medication that has been approved by the FDA for the treatment of phenylketonuria (PKU) in adults. PKU is a rare genetic disorder that affects the body’s ability to break down the amino acid phenylalanine, leading to a buildup of this substance in the blood. This buildup can cause serious health problems, including intellectual disabilities, seizures, and behavioral issues.

Palynziq works by replacing the missing enzyme that is needed to break down phenylalanine in individuals with PKU. By doing so, it helps to reduce the levels of phenylalanine in the blood, which can help to prevent the serious complications associated with this disorder.

It is important to note that Palynziq is not a cure for PKU, but it can significantly improve the quality of life for individuals living with this condition. It is typically administered as a subcutaneous injection once daily, and patients may need to undergo regular monitoring of their blood phenylalanine levels to ensure that the medication is working effectively.

As with any medication, Palynziq can cause side effects, including injection site reactions, allergic reactions, and changes in mood or behavior. It is important for patients to discuss any concerns or potential side effects with their healthcare provider before starting treatment with Palynziq.

Overall, Palynziq represents a major advancement in the treatment of PKU and offers hope for individuals living with this challenging condition. If you or a loved one has been diagnosed with PKU, talk to your healthcare provider to see if Palynziq may be a suitable treatment option for you.

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The information provided on RxDB.net is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional, such as a doctor or pharmacist, for any questions or concerns regarding your health, medications, or medical conditions. Reliance on any information provided on this website is solely at your own risk. RxDB.net does not provide medical or pharmaceutical services and is not liable for any decisions made based on the information contained herein.

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