Dornase alfa, also known by its brand name Pulmozyme, is a medication commonly used in the treatment of cystic fibrosis. This drug is a recombinant human deoxyribonuclease enzyme that works by breaking down the thick, sticky mucus that can build up in the lungs of individuals with cystic fibrosis.

By targeting the DNA in the mucus, Dornase alfa helps to thin out the mucus, making it easier for patients to cough up and clear from their airways. This can help to improve lung function, reduce the frequency of respiratory infections, and ultimately improve the quality of life for individuals with cystic fibrosis.

Dornase alfa is typically administered via a nebulizer, which allows the medication to be inhaled directly into the lungs where it can work most effectively. It is important for patients to follow their healthcare provider’s instructions for using Dornase alfa, including the correct dosage and frequency of administration.

As with any medication, Dornase alfa may cause side effects in some individuals. Common side effects may include voice alteration, sore throat, and chest pain. It is important for patients to discuss any concerns or side effects with their healthcare provider.

Overall, Dornase alfa has been shown to be an effective treatment for individuals with cystic fibrosis, helping to improve lung function and reduce respiratory symptoms. If you or a loved one has cystic fibrosis, talk to your healthcare provider to see if Dornase alfa may be a suitable treatment option for you.