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Blinatumomab: Benefits, Reviews, Info, Side Effects!
Rx Details
Blinatumomab
Blincyto, AMG103
Blinatumomab
Prescription
Antibody
Drugs
Prescription Only
treatment of acute lymphoblastic leukemia, targeting CD19-positive B-cell precursor leukemia, improving survival rates, reducing minimal residual disease, potential for use in relapsed or refractory cases, immunotherapy approach, engaging T-cells to attack cancer cells
Abdominal Pain, Back Pain, Chills, Constipation, Cough, Decreased Appetite, Diarrhea, Dizziness, Edema, Elevated Liver Enzymes, Fatigue, Fever, Headache, Infections, Infusion Reactions, Insomnia, Low Blood Cell Counts, Nausea, Rash, Tremor, Weight Gain
Blinatumomab is a medication used to treat certain types of leukemia. The dosage of blinatumomab can vary based on factors such as the patient’s weight, the specific condition being treated, and the treatment phase. Typically, blinatumomab is administered as a continuous intravenous infusion over a period of days. For adults with acute lymphoblastic leukemia (ALL), the usual dosing schedule is as follows: – **Cycle 1**: 9 micrograms per day for the first 7 days, followed by 28 micrograms per day for the remaining 21 days. – **Subsequent Cycles**: 28 micrograms per day for 28 days. Each cycle is usually followed by a 14-day treatment-free interval. However, the exact dosage and schedule can vary, and it is crucial for patients to follow the specific instructions provided by their healthcare provider. Always consult with a healthcare professional for the most accurate and personalized dosing information.
Acute lymphoblastic leukemia
Blinatumomab has a generally well-tolerated safety profile.
No Interactions Reported
$10,000 – $15,000
$16,000 for a 1.25 mg vial.

A Synopsis of

Blinatumomab

Blinatumomab is a novel immunotherapy drug that has shown promising results in the treatment of certain types of leukemia. This medication works by harnessing the power of the body’s own immune system to target and destroy cancer cells.

Blinatumomab is specifically approved for the treatment of B-cell precursor acute lymphoblastic leukemia (ALL) in both adults and children. It is a type of medication known as a bispecific T-cell engager (BiTE) antibody, which works by binding to both cancer cells and T-cells, bringing them into close proximity and allowing the T-cells to recognize and attack the cancer cells.

Clinical trials have shown that blinatumomab can induce remission in patients with relapsed or refractory ALL, even in cases where other treatments have failed. It has also been shown to improve overall survival rates in patients with this aggressive form of leukemia.

As with any medication, blinatumomab does come with potential side effects. These can include flu-like symptoms, fever, headaches, and low blood cell counts. It is important for patients to be closely monitored by their healthcare team while receiving this medication.

Overall, blinatumomab represents a significant advancement in the treatment of leukemia and offers hope to patients who may have limited treatment options. If you or a loved one has been diagnosed with B-cell precursor ALL, I encourage you to speak with your healthcare provider about whether blinatumomab may be a suitable treatment option for you.

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