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Asfotase alfa: Benefits, Reviews, Info, Side Effects!
Rx Details
Asfotase alfa
Strensiq, ENB-0040
Asfotase alfa
Prescription
Enzyme
Drugs
Prescription Only
improves bone mineralization, reduces skeletal abnormalities, enhances physical function, decreases pain, improves respiratory function, increases survival rates in patients with hypophosphatasia
Abdominal Pain, Chills, Diarrhea, Fatigue, Fever, Headache, Hypersensitivity Reactions, Injection Site Reactions, Joint Pain, Muscle Pain, Nausea, Rash, Respiratory Infections, Vomiting
Asfotase alfa is a medication used to treat hypophosphatasia, a rare metabolic bone disorder. The dosage of asfotase alfa is individualized based on the patient’s weight and the severity of the condition. Typically, the recommended dosage is: – 2 mg/kg of body weight administered subcutaneously three times per week, or – 1 mg/kg of body weight administered subcutaneously six times per week. It’s important to note that the exact dosage and frequency should be determined by a healthcare professional based on the specific needs of the patient. Always consult with a healthcare provider for accurate dosing information.
Hypophosphatasia
Safety profile of asfotase alfa is generally favorable.
No Interactions Reported
$10,000 – $20,000
$6,000 per vial.

A Synopsis of

Asfotase alfa

Asfotase alfa is a medication that is used to treat a rare genetic disorder known as hypophosphatasia (HPP). This condition is characterized by a deficiency of an enzyme called tissue-nonspecific alkaline phosphatase (TNSALP), which leads to the accumulation of certain substances in the body that can cause bone and tooth abnormalities.

Asfotase alfa works by replacing the missing enzyme in patients with HPP, helping to break down these harmful substances and improve bone mineralization. It is administered through injections under the skin, typically on a regular basis as prescribed by a healthcare provider.

It is important to follow the dosing schedule and instructions provided by your healthcare team to ensure the best possible outcomes with this medication. Asfotase alfa has been shown to be effective in improving bone mineralization, reducing pain and fractures, and improving overall quality of life in patients with HPP.

Like any medication, asfotase alfa may cause side effects in some individuals. These can include injection site reactions, allergic reactions, and other less common side effects. It is important to discuss any concerns or potential side effects with your healthcare provider.

Overall, asfotase alfa is a valuable treatment option for individuals with HPP, offering the potential to improve bone health and quality of life. If you or a loved one has been diagnosed with HPP, talk to your healthcare provider about whether asfotase alfa may be a suitable treatment option for you.

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