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Alteplase, Recombinant: Benefits, Reviews, Info, Side Effects!
Rx Details
Alteplase, Recombinant
Activase, TPA, tissue plasminogen activator
Alteplase
Prescription
Thrombolytic
Drugs
Prescription Only
clot dissolution, improved blood flow, reduced risk of stroke damage, treatment of acute ischemic stroke, treatment of pulmonary embolism, treatment of myocardial infarction
Allergic Reactions, Back Pain, Bleeding, Bleeding Gums, Bruising, Dizziness, Fever, Headache, Hypotension, Irregular Heartbeat, Muscle Pain, Nausea, Nosebleeds, Rash, Vomiting
Alteplase, recombinant, commonly known as tissue plasminogen activator (tPA), is a medication used to treat acute ischemic stroke, myocardial infarction (heart attack), and pulmonary embolism. The dosage of alteplase varies depending on the condition being treated: 1. **Acute Ischemic Stroke**: – The recommended dose is 0.9 mg/kg (maximum of 90 mg total), with 10% of the total dose given as an initial intravenous bolus over 1 minute, followed by the remaining 90% infused over 60 minutes. 2. **Acute Myocardial Infarction**: – The total dose is typically 100 mg administered over 1.5 hours. This is usually given as 15 mg as an initial intravenous bolus, followed by 50 mg over the next 30 minutes, and then 35 mg over the following 60 minutes. 3. **Pulmonary Embolism**: – The usual dose is 100 mg administered over 2 hours. In some cases, a bolus of 10 mg may be given over 1-2 minutes, followed by the remaining 90 mg over 2 hours. It’s important to note that the administration of alteplase should be done under strict medical supervision, and the exact dosage may vary based on specific patient factors and institutional protocols. Always consult a healthcare professional for precise dosing and administration.
Acute ischemic stroke, pulmonary embolism, myocardial infarction
Alteplase, Recombinant has a favorable safety profile.
Anticoagulants, antiplatelet drugs, thrombolytics
$1,000 – $2,000
$1200

A Synopsis of

Alteplase, Recombinant

Alteplase, also known as recombinant tissue plasminogen activator (rt-PA), is a thrombolytic medication used in the treatment of acute ischemic stroke, pulmonary embolism, and myocardial infarction. This medication works by dissolving blood clots that are blocking blood flow to vital organs, thereby restoring circulation and preventing further damage.

Alteplase is administered intravenously and should be given as soon as possible after the onset of symptoms in order to maximize its effectiveness. It is crucial to follow the dosing instructions provided by your healthcare provider to ensure the best possible outcome.

As with any medication, there are potential risks and side effects associated with alteplase. These may include bleeding, allergic reactions, and rare but serious complications such as intracranial hemorrhage. It is important to discuss these risks with your healthcare provider before starting treatment with alteplase.

It is also important to inform your healthcare provider of any other medications or supplements you are taking, as they may interact with alteplase and affect its effectiveness. Additionally, certain medical conditions such as recent surgery, uncontrolled hypertension, or a history of bleeding disorders may impact the safety and efficacy of this medication.

Overall, alteplase is a valuable tool in the treatment of acute thrombotic events and has been shown to significantly improve outcomes when administered promptly and appropriately. If you have any questions or concerns about alteplase or its use, do not hesitate to speak with your healthcare provider for more information.

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The information provided on RxDB.net is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional, such as a doctor or pharmacist, for any questions or concerns regarding your health, medications, or medical conditions. Reliance on any information provided on this website is solely at your own risk. RxDB.net does not provide medical or pharmaceutical services and is not liable for any decisions made based on the information contained herein.

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