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Defibrotide: Benefits, Reviews, Info, Side Effects!
Rx Details
Defibrotide
Defibrotide
Prescription
Medication
Drugs
Prescription Only
protection of endothelial cells, reduction of inflammation, prevention of blood clot formation, treatment of severe hepatic veno-occlusive disease, improvement of blood flow, reduction of tissue damage
Diarrhea, Fever, Headache, Hemorrhage, Hypotension, Nausea, Vomiting
Defibrotide is a medication used primarily to treat severe hepatic veno-occlusive disease (VOD) in patients who have undergone hematopoietic stem-cell transplantation. The typical dosage for defibrotide is 6.25 mg/kg administered intravenously every 6 hours, totaling 25 mg/kg per day. However, the exact dosage may vary based on specific patient needs and medical guidance, so it is important to follow the prescribing physician’s instructions.
Hepatic veno-occlusive disease
Generally well-tolerated, with common side effects including nausea, vomiting, and diarrhea.
No Interactions Reported
$1,000 – $2,000
$1,500 for a 200 mg vial.

A Synopsis of

Defibrotide

Defibrotide is a unique medication that has shown promising results in the treatment of certain conditions, particularly in the field of hematology. This drug is derived from single-stranded DNA and works by preventing blood clots from forming in small blood vessels, which can be a common complication in certain conditions such as hepatic veno-occlusive disease (VOD) or thrombotic microangiopathy (TMA).

Defibrotide has been studied extensively in clinical trials and has been shown to be effective in reducing the risk of blood clots and improving overall outcomes in patients with these conditions. It is believed to work by promoting the breakdown of clots and improving blood flow in the affected areas, ultimately leading to better outcomes for patients.

As with any medication, there are potential side effects associated with defibrotide, including bleeding, low blood pressure, and allergic reactions. It is important for patients to discuss these risks with their healthcare provider before starting treatment with defibrotide.

Overall, defibrotide is a promising medication that has shown great potential in the treatment of certain conditions. If you or a loved one has been diagnosed with a condition that may benefit from treatment with defibrotide, be sure to speak with your healthcare provider about whether this medication may be right for you. Your healthcare provider can provide you with more information about the risks and benefits of defibrotide and help you make an informed decision about your treatment options.

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