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Idursulfase: Benefits, Reviews, Info, Side Effects!
Rx Details
Idursulfase
Elaprase, Recombinant human iduronate-2-sulfatase
Idursulfase
Prescription
Enzyme
Drugs
Prescription Only
enzyme replacement therapy for Hunter syndrome, reduces glycosaminoglycan accumulation, improves walking capacity, enhances respiratory function, decreases liver and spleen size, improves joint mobility, reduces urinary glycosaminoglycan levels
Abdominal Pain, Allergic Reactions, Back Pain, Chest Pain, Chills, Cough, Diarrhea, Dizziness, Fatigue, Fever, Flushing, Headache, Itching, Joint Pain, Muscle Pain, Nausea, Rash, Shortness Of Breath, Sore Throat, Swelling, Vomiting
Idursulfase is an enzyme replacement therapy used primarily to treat Hunter syndrome (Mucopolysaccharidosis II). The average dosage for idursulfase is typically based on the patient’s body weight. The standard recommended dose is 0.5 mg per kilogram of body weight, administered once weekly as an intravenous infusion. However, the exact dosage and treatment regimen should always be determined by a healthcare professional based on the individual needs of the patient.
Hunter syndrome (mucopolysaccharidosis ii), enzyme replacement therapy
Generally well-tolerated with mild to moderate side effects.
No Interactions Reported
$10,000 – $20,000
$10,000 per vial.

A Synopsis of

Idursulfase

Idursulfase is a medication that is used to treat a rare genetic disorder known as Hunter syndrome, also called mucopolysaccharidosis II (MPS II). This condition is caused by a deficiency of the enzyme iduronate-2-sulfatase, which leads to the accumulation of certain substances in the body’s cells and tissues.

Idursulfase works by replacing the missing enzyme in patients with Hunter syndrome, helping to break down and remove the accumulated substances. This can help to improve symptoms such as joint stiffness, organ enlargement, and respiratory issues that are common in individuals with MPS II.

It is important to note that idursulfase is administered through intravenous infusion, typically in a clinical setting by a healthcare professional. The dosage and frequency of treatment will be determined by your healthcare provider based on your individual needs and response to the medication.

As with any medication, there may be potential side effects associated with idursulfase. These can include allergic reactions, fever, headache, and nausea. It is important to discuss any concerns or potential side effects with your healthcare provider.

Overall, idursulfase has been shown to be an effective treatment for individuals with Hunter syndrome, helping to improve quality of life and manage symptoms associated with this rare genetic disorder. If you or a loved one has been diagnosed with MPS II, speak with your healthcare provider to see if idursulfase may be a suitable treatment option.

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