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Tolvaptan: Benefits, Reviews, Info, Side Effects!
Rx Details
Tolvaptan
Samsca, Jinarc
Tolvaptan
Prescription
Diuretic
Drugs
Prescription Only
Treatment of hyponatremia, management of autosomal dominant polycystic kidney disease, reduction of kidney cyst growth, delay in kidney function decline.
Dehydration, Dizziness, Dry Mouth, Fatigue, Frequent Urination, Increased Thirst, Liver Damage, Low Blood Pressure, Nausea
Tolvaptan is a medication used primarily to treat hyponatremia (low blood sodium levels) associated with conditions like heart failure and the syndrome of inappropriate antidiuretic hormone secretion (SIADH), as well as to slow kidney function decline in adults at risk of rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). The dosage of tolvaptan can vary based on the condition being treated: 1. **For Hyponatremia (SIADH, heart failure):** – The initial dose is typically 15 mg once daily. – The dose may be increased to 30 mg once daily, and then to 60 mg once daily, as needed and tolerated, to achieve the desired level of serum sodium. 2. **For Autosomal Dominant Polycystic Kidney Disease (ADPKD):** – The initial dose is usually 60 mg per day, divided into two doses: 45 mg in the morning and 15 mg in the afternoon. – The dose may be increased to 90 mg per day (60 mg in the morning and 30 mg in the afternoon) and then to 120 mg per day (90 mg in the morning and 30 mg in the afternoon), based on tolerability and response. It’s important to note that the exact dosage should be determined by a healthcare provider, taking into account the specific needs and health status of the patient. Additionally, tolvaptan treatment requires careful monitoring of liver function and serum sodium levels.
Hyponatremia, autosomal dominant polycystic kidney disease
Tolvaptan has a well-established safety profile.
Liver injury, dehydration, hypernatremia, hypovolemia, increased risk of bleeding
$200 – $500
$1,200 for a 30day supply.

A Synopsis of

Tolvaptan

Tolvaptan is a medication that belongs to a class of drugs known as vasopressin receptor antagonists. It is commonly used to treat hyponatremia, a condition characterized by low levels of sodium in the blood. Tolvaptan works by blocking the action of vasopressin, a hormone that regulates water retention in the body.

Patients with conditions such as heart failure, liver cirrhosis, and syndrome of inappropriate antidiuretic hormone secretion (SIADH) may benefit from tolvaptan therapy. By increasing urine output and promoting the excretion of excess water, tolvaptan helps to restore normal sodium levels in the blood.

It is important to follow your healthcare provider’s instructions when taking tolvaptan. Dosage and duration of treatment will vary depending on the underlying condition being treated. It is also important to monitor sodium levels regularly while taking tolvaptan to ensure that they remain within a safe range.

As with any medication, tolvaptan may cause side effects in some individuals. Common side effects may include thirst, dry mouth, and increased urination. More serious side effects such as liver problems or allergic reactions are rare but should be reported to your healthcare provider immediately.

If you have any questions or concerns about tolvaptan or its use, do not hesitate to speak with your healthcare provider. They can provide you with more information about the medication and help you determine if it is the right treatment option for you. Remember to always take medications as prescribed and to report any unusual symptoms or side effects to your healthcare provider promptly.

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