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Lumacaftor & Ivacaftor: Benefits, Reviews, Info, Side Effects!
Rx Details
Lumacaftor & Ivacaftor
Orkambi, Luma, Ivacaftor/Lumacaftor
Lumacaftor & Ivacaftor
Prescription
Medication
Drugs
Prescription Only
improves lung function, reduces pulmonary exacerbations, improves weight gain, enhances quality of life, targets underlying cause of cystic fibrosis, suitable for specific CFTR mutations, reduces sweat chloride levels
Abnormal Breathing Sounds, Common Cold Symptoms, Diarrhea, Fatigue, Gas, Headache, Increased Liver Enzymes, Menstrual Irregularities, Nausea, Rash, Shortness Of Breath, Upper Respiratory Tract Infection
Lumacaftor and ivacaftor are medications used in combination to treat cystic fibrosis in patients with specific genetic mutations. The average dosage for this combination therapy, marketed under the brand name Orkambi, typically depends on the patient’s age and weight. For patients aged 6 years and older who weigh 25 kg or more, the usual dosage is: – Lumacaftor 200 mg/ivacaftor 125 mg: Two tablets taken orally every 12 hours. For patients aged 6 years and older who weigh less than 25 kg, the dosage is adjusted accordingly, often involving a lower strength formulation. It’s important to follow the specific dosage instructions provided by a healthcare professional, as they may adjust the dosage based on individual needs and response to treatment. Always consult with a healthcare provider for the most accurate and personalized dosage information.
Cystic fibrosis
Generally well-tolerated with common side effects including respiratory symptoms and gastrointestinal issues.
May interact with certain medications, such as strong CYP3A inducers or inhibitors
$3,000 – $5,000
$23,269.60

A Synopsis of

Lumacaftor & Ivacaftor

Lumacaftor and Ivacaftor are two medications that are commonly used in the treatment of cystic fibrosis. Lumacaftor works by helping to correct the defective protein that causes cystic fibrosis, while Ivacaftor helps to improve the function of the protein once it has been corrected.

These two medications are often used together in a combination therapy to provide the best possible outcomes for patients with cystic fibrosis. By targeting different aspects of the disease, Lumacaftor and Ivacaftor work together to improve lung function, reduce the frequency of respiratory infections, and improve overall quality of life for patients.

It is important to note that Lumacaftor and Ivacaftor are prescription medications and should only be taken under the supervision of a healthcare provider. Your doctor will determine the appropriate dosage and frequency of these medications based on your individual needs and medical history.

As with any medication, there may be potential side effects associated with Lumacaftor and Ivacaftor. Common side effects may include nausea, diarrhea, and respiratory symptoms. It is important to discuss any concerns or side effects with your healthcare provider.

Overall, Lumacaftor and Ivacaftor have been shown to be effective in improving outcomes for patients with cystic fibrosis. If you or a loved one has been diagnosed with cystic fibrosis, talk to your doctor about whether Lumacaftor and Ivacaftor may be a suitable treatment option for you.

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